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4 results for “elimination”

Formulae (4)

t_{1/2} = \frac{0.693}{k_e}

Time for the plasma concentration of a drug to fall to half its initial value.

C_{ss} = \frac{F \times D}{CL \times \tau}

Average plasma drug concentration when intake and elimination are balanced.

CL = k_e \times V_d

Volume of plasma completely cleared of a drug per unit time.

C(t) = C_0 \times e^{-k_e t}

Drug concentration decreases exponentially — a constant fraction is eliminated per unit time.