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5 results for “dose”

Formulae (5)

LD = \frac{C_{target} \times V_d}{F}

Initial higher dose to rapidly achieve the desired plasma concentration.

MD = C_{ss} \times CL \times \tau

Recurring dose needed to sustain the steady-state concentration.

F = \frac{AUC_{oral}}{AUC_{IV}} \times 100

Fraction of an oral dose that reaches systemic circulation compared with an IV dose.

TI = \frac{TD_{50}}{ED_{50}}

Ratio of the dose causing toxicity to the effective dose — a safety measure for drugs.

D = d \times W

Calculate the total dose from a per-kilogram dosing rate — common in paediatrics.